Erfahren Sie mehr über die Fortschritte bei der Knorpelreparatur mit MACT. Greifen Sie auf mehr als 20 Studien zu, sehen Sie sich Videos zu Operationstechniken an und laden Sie medizinische Informationen und Patienteninformationen herunter.
2022
Angele P, Zellner J, Schröter S, Flechtenmacher J, Fritz J, Niemeyer P.
Biological Reconstruction of Localized Full-Thickness Cartilage Defects of the Knee: A Systematic Review of Level 1 Studies with a Minimum Follow-Up of 5 Years. Cartilage. 2022 Dec; 13(4): 5-18. DOI: 10.1177/19476035221129571
2024
Eichinger M, Henninger B, Petry B, Schuster P, Herbst E, Wagner M, Rosenberger R, Mayr R.
Treatment of cartilage defects in the patellofemoral joint with matrix-associated autologous chondrocyte implantation effectively improves pain, function, and radiological outcomes after 5-7 years. Arch Orthop Trauma Surg. 2024 Apr; 144(4): 1655-1665. DOI: 10.1007/s00402-023-05179-0
2024
Weishorn J, Wiegand J, Zietzschmann S, Koch KA, Rehnitz C, Renkawitz T, Walker T, Bangert Y.
Factors Influencing Long-term Outcomes After Matrix-Induced Autologous Chondrocyte Implantation: Long-term Results at 10 Years. Am J Sports Med. 2024 Sep; 52(11): 2782-2791. DOI: 10.1177/03635465241270152
2016
Niemeyer P, Albrecht D, Andereya S, Angele P, et al.
Autologous chondrocyte implantation (ACI) for cartilage defects of the knee: A guideline by the working group "Clinical Tissue Regeneration" of the German Society of Orthopaedics and Trauma (DGOU), The Knee, Review 23, 426-435 (2016). DOI: 10.1016/j.knee.2016.02.001
2016
H Bretschneider, M Stiehler, A Hartmann, E Boger, C Osswald, J Mollenhauer, C Gaissmaier, K-P Günther
Characterization of primary chondrocytes harvested from hips with femoroacetabular impingement. Osteoarthritis Cartilage. 2016 Sep; 24(9): 1622-8. DOI: 10.1016/j.joca.2016.04.011
2022
Ehmann YJ, Zuche L, Schmitt A, Berthold DP, Rupp MC, Muench LN, Otto A, Woertler K, Imhoff AB, Mehl J.
Excellent clinical and radiological outcomes after both open flake refixation and autologous chondrocyte implantation following acute patella dislocation and concomitant flake fractures. Knee Surg Sports Traumatol Arthrosc. 2022 Feb 26. DOI: 10.1007/s00167-022-06899-3
2021
Niethammer TR, Altmann D, Holzgruber M, Goller S, Fischer A, Müller PE.
Third generation autologous chondrocyte implantation is a good treatment option for athletic persons. Knee Surg Sports Traumatol Arthrosc. 2021 Apr; 29(4): 1215-1223. DOI: 10.1007/s00167-020-06148-5
2021
Niethammer TR, Gallik D, Chevalier Y, Holzgruber M, Baur-Melnyk A, Müller PE, Pietschmann MF.
Effect of the defect localization and size on the success of third-generation autologous chondrocyte implantation in the knee joint. Int Orthop. 2021 Jun; 45(6): 1483-1491. DOI: 10.1007/s00264-020-04884-4
2021
Angele P, Docheva D, Pattappa G, Zellner J.
Cell-based treatment options facilitate regeneration of cartilage, ligaments and meniscus in demanding conditions of the knee by a whole joint approach. Knee Surg Sports Traumatol Arthrosc. 2021 Mar 5. DOI: 10.1007/s00167-021-06497-9
2021
Juras V, Szomolanyi P, Janáčová V, Kirner A, Angele P, Trattnig S.
Differentiation of Cartilage Repair Techniques Using Texture Analysis from T2 Maps. Cartilage. 2021 Dec; 13 (1_suppl): 718S-728S. DOI: 10.1177/19476035211029698
2020
Niethammer TR, Gallik D, Chevalier Y et al.
Effect of the defect localization and size on the success of third-generation autologous chondrocyte implantation in the knee joint. Int Orthop.2021 Jun; 45(6): 1483-1491. Epub 2020 Dec 6. DOI: 10.1007/s00264-020-04884-4
2020
Gersing AS, Feuerriegel G, Holwein C et al.
T2-relaxation time of cartilage repair tissue is associated with bone remodeling after spongiosa-augmented matrix-associated autologous chondrocyte implantation. Osteoarthritis Cartilage. 2019 Jan; 27(1): 90-98. DOI: 10.1016/j.joca.2018.08.023
2020
Niethammer TR, Altmann D, Holzgruber M, Gülecyüz MF, Notohamiprodjo S, Baur-Melnyk A, Müller PE.
Patient-Reported and Magnetic Resonance Imaging Outcomes of Third-Generation Autologous Chondrocyte Implantation After 10 Years. Arthroscopy. 2020 Jul;36(7): 1928-1938. DOI: 10.1016/j.arthro.2020.03.009
2017
Niethammer TR, Holzgruber M, Gülecyüz MF, Weber P, Pietschmann MF, Müller PE.
Matrix based autologous chondrocyte implantation in children and adolescents: a match paired analysis in a follow-up over three years post-operation. Int Orthop. 2017 Feb; 41(2): 343-350. DOI: 10.1007/s00264-016-3321-1
2017
Zellner J, Grechenig S, Pfeifer CG, Krutsch W, Koch M, Welsch G, Scherl M, Seitz J, Zeman F, Nerlich M, Angele P.
Clinical and Radiological Regeneration of Large and Deep Osteochondral Defects of the Knee by Bone Augmentation Combined With Matrix-Guided Autologous Chondrocyte Transplantation. Am J Sports Med. 2017 Nov; 45(13): 3069-3080. DOI: 10.1177/0363546517717679
2016
Niethammer TR, Limbrunner K, Betz OB, Gülecyüz MF, Pietschmann MF, Feist M, Müller PE.
Analysis of the autologous chondrocyte quality of matrix-based autologous chondrocyte implantation in the knee joint. Int Orthop. 2016 Jan; 40(1): 205-12. DOI: 10.1007/s00264-015-2825-4
2015
Dell'Osso G, Ghilardi M, Bottai V, Bugelli G, Guido G, Giannotti S.
Up-to-date Review and Cases Report on Chondral Defects of Knee Treated by ACI Technique: Clinical-instrumental and Histological Results. Surg Technol Int. 2015 May; 26: 317-23. PMID: 26055026
2014
Zak L, Albrecht C, Wondrasch B, Widhalm H, Vekszler G, Trattnig S, Marlovits S, Aldrian S.
Results 2 Years After Matrix-Associated Autologous Chondrocyte Transplantation Using the Novocart 3D Scaffold: An Analysis of Clinical and Radiological Data. Am J Sports Med. 2014 Jul; 42(7): 1618-27. DOI: 10.1177/0363546514532337
2014
Niethammer TR, Safi E, Ficklscherer A, Horng A, Feist M, Feist-Pagenstert I, Jansson V, Pietschmann MF, Müller PE.
Graft maturation of autologous chondrocyte implantation: magnetic resonance investigation with T2 mapping. Am J Sports Med. 2014 Sep; 42(9): 2199-204. DOI: 10.1177/0363546514538756
2013
Zellner J, Angele P, Zeman F, Kujat R, Nerlich M
Is the transplant quality at the time of surgery adequate for matrix-guided autologous cartilage transplantation? A pilot study. Clin Orthop Relat Res. 2013 Sep; 471(9): 2852-61. DOI: 10.1007/s11999-013-2958-y
2012
Pietschmann MF, Niethammer TR, Horng A, Gülecyüz MF, Feist-Pagenstert I, Jansson V, Müller PE.
The incidence and clinical relevance of graft hypertrophy after matrix-based autologous chondrocyte implantation. Am J Sports Med. 2012Jan; 40(1): 68-74. DOI: 10.1177/0363546511424396
2011
Nuernberger S, Cyran N, Albrecht C, Redl H, Vécsei V, Marlovits S.
The influence of scaffold architecture on chondrocyte distribution and behavior in matrix-associated chondrocyte transplantation grafts. Biomaterials. 2011 Feb; 32(4): 1032-40. DOI: 10.1016/j.biomaterials.2010.08.100
2011
Ochs BG, Müller-Horvat C, Albrecht D, Schewe B, Weise K, Aicher WK, Rolauffs B.
Remodeling of articular cartilage and subchondral bone after bone grafting and matrix-associated autologous chondrocyte implantation for osteochondritis dissecans of the knee. Am J Sports Med. 2011 Apr; 39(4): 764-73. DOI: 10.1177/0363546510388896
2022
Niemeyer P, Hanus M, Belickas J, László T, Gudas R, Fiodorovas M, Cebatorius A, Pastucha M, Hoza P, Magos K, Izadpanah K, Paša L, Vásárhelyi G, Sisák K, Mohyla M, Farkas C, Kessler O, Kybal S, Spiro B, Köhler A, Kirner A, Trattnig S, Gaissmaier C.
Treatment of Large Cartilage Defects in the Knee by Hydrogel-Based Autologous Chondrocyte Implantation: Two-Year Results of a Prospective, Multicenter, Single-Arm Phase III Trial. 2022 Jan-Mar; 13(1). DOI: 10.1177/19476035221085146
2021
Blanke F, Oehler N, Haenle M, Lenz R, Vogt S, Tischer T.
All-Arthroscopic Hydrogel-Based Autologous Chondrocyte Transplantation in the Knee Joint: Good Clinical and Magnetic Resonance Imaging Outcome After 24 Months. Arthroscopy. 2021 Jun; 37(6): 1892-1899. DOI: 10.1016/j.arthro.2021.01.038
2020
Bretschneider H, Trattnig S, Landgraeber S, Hartmann A, Günther KP, Dienst M, Schröder J, Fickert S.
Arthroscopic matrix-associated, injectable autologous chondrocyte transplantation of the hip: significant improvement in patient-related outcome and good transplant quality in MRI assessment. Knee Surg Sports Traumatol Arthrosc. 2020 Apr; 28(4): 1317-1324. DOI: 10.1007/s00167-019-05466-7
2019
Schlumberger M, Schuster P, Bülow HJ, Mayer P, Eichinger M, Richter J.
Arthroscopic autologous chondrocyte implantation in the knee with an in situ crosslinking matrix: minimum 4-year clinical results of 15 cases and 1 histological evaluation. Arch Orthop Trauma Surg. 2019 Nov;139(11):1607-1615.DOI: 10.1007/s00402-019-03243-2
2018
Thier S, Baumann F, Weiss C, Fickert S.
Feasibility of arthroscopic autologous chondrocyte implantation in the hip using an injectable hydrogel. Hip Int. 2018 Jul; 28(4): 442-449. DOI: 10.5301/hipint.5000580
Die folgenden Videoclips enthalten Informationen zu NOVOCART® 3D (kollagenbasierte Knorpelzelltransplantation) und NOVOCART® Inject (gelbasierte Knorpelzelltransplantation). Bitte entnehmen Sie Details zur Anwendung, zu Risiken und Nebenwirkungen den unten stehenden Dokumenten.
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