Accelerating Cell Therapy
With over 20 years of tissue engineering experience, TETEC AG develops personalised cell therapies for knee cartilage repair to help preserve mobility, independence, and quality of life over time where regenerative medicine is the new standard of care. Learn more by selecting the information that best suits you.
The Future of Knee Cartilage Repair
As part of Octane Medical Group, we're working to bring regenerative medicine closer to the patient—by enabling faster, localized production of autologous knee cartilage grafts. Our goal is to one day deliver personalised cell therapy at the point of care and help establish it as a standard part of treatment.
Knee Cartilage Repair With Cells
TETEC offers two distinct approaches for knee cartilage repair—each using the patient's own cells: Injectable MACT (Matrix-Associated Autologous Chondrocyte Transplantation) and MACT.
Injectable MACT Procedure
Injectable MACT is a cell-based cartilage-repair procedure in which a patient's own cartilage cells are combined with a hydrogel and implanted into a focal knee cartilage defect [1]. In clinical studies and earlier publications, this approach is also described as hydrogel-based ACI or injectable MACI.
- Injectable hydrogel containing the patient's cartilage cells
- Implanted arthroscopically through small incisions
- Available as outpatient or inpatient care, as appropriate
MACT Procedure
In MACT, the patient's own cells are placed on a collagen scaffold and implanted for the treatment of focal knee cartilage defects [2].
- Patch-like scaffold seeded with the patient's cartilage cells
- Implanted through a standard surgical incision
- Available as outpatient or inpatient care, as appropriate
Performed in Germany
More than 30,000 Autologous Chondrocyte Implantation (ACI) procedures—including Injectable MACT and MACT—have been performed to date in Germany by TETEC, using autologous cells to treat focal knee defects [3].
Our Network of Excellence
From global scientific societies to leading academic and industry partners, TETEC is recognized and trusted by organisations advancing the future of cartilage repair.
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Grow Your Career at TETEC
Join TETEC and help shape the future of regenerative medicine. We offer roles in research, production, and quality—focused on advancing personalised cell therapies for knee cartilage repair.
1. TETEC AG. Fachinformation NOVOCART Inject. Reutlingen (DE): TETEC AG; 2022. Stand der Information: 12/2022. PEI.A.11763.01.1.
2. TETEC AG. Fachinformation NOVOCART 3D. Reutlingen (DE): TETEC AG; 2023. Stand der Information: 11/2023. PEI.A.11511.01.1.
3. Data on File. TETEC AG. Internal registry and reporting of Injectable MACT and MACT procedures performed in Germany. Reutlingen (DE): TETEC AG; 2025.